Cell lines are crucial in biomedical research, serving as models for different scientific experiments. However, a concerning problem arises due to cross-contamination and misidentification, impacting up to 35% of cell line cultures. Such errors lead to invalid analysis data and wasted resources, affecting scientific progress. Scientists use STR profiling, a simple molecular method for human & mouse Cell Line Authentication, to mitigate these risks. Regular STR profiling in cell culture management can detect errors and ensure authentic experimental results. By adopting this method, researchers can defend the integrity of their analyses, leading to more accurate and meaningful scientific discoveries.
Kinds of Errors Detected in Cell Line Authentication
Cell line authentication seeks to recognize errors in the identity of cultured cell lines. Some common kinds of errors detected in cell line authentication are:
- Misidentification: It happens when a cell line is inaccurately identified or labeled. It may involve using the incorrect source for a cell line. Misidentification errors can result from lab mix-ups or wrong record-keeping.
- Cross-Contamination Errors: It occurs when a cell line becomes contaminated with other cells, fungi, bacteria, etc. Contaminants can vary the genetic profile of the cell line, leading to authentication differences.
- Genetic Drift: Eventually, the cell line can fully lose its identity & drift genetically into a different cell type, affecting the research or test results.
Significance of Cell Line Authentication Test
Cell line authentication tests are important in various fields, such as biotechnology, medicine, scientific research, & forensic investigations. Here are some key factors why cell line authentication tests in India are vital:
- Research Integrity: Assuring the authenticity of cell lines used in analysis is critical for keeping the integrity of scientific studies. Contaminated or misidentified cell lines can lead to incorrect research findings.
- Data Reliability: Accurate cell lines generate reliable & reproducible experimental data. Researchers depend on the thickness of cell lines to draw meaningful findings and create scientific advances.
- Quality Control: Cell line authentication is critical for quality control in the pharmaceutical & biotechnology industries. Accurate cell lines are important for developing and producing effective therapeutics, biologics, and vaccines.
- Patient Safety: In medical and clinical applications, confirming the authenticity of cell lines used in diagnostics therapies is vital. Misidentified or contaminated cells can lead to negative health effects.
- Regulatory Obedience: Many regulatory powers need cell lines authentication for product approval and safety guidelines. Compliance with these rules is vital for market approval.
Why Choose DNA Forensics Laboratory Pvt. Ltd.?
Getting cell line authentication tests in India can be a crucial decision, provided the significance & sensitivity of a project. DNA Forensics Laboratory Pvt. Ltd. is one of India’s best & most well-reputed companies for DNA testing. They offer accurate, reliable, & accredited Cell Line Authentication in India at a competitive price. Their testing facility is accredited by NABL. It’s the only Indian company in India that provides legal DNA tests for various courts of law.
They always used cutting-edge technology & standardized techniques for this testing. Their clients are from various reputable research institutes, pharmaceutical companies, biotechnology companies, etc. It detects cross-contamination, misidentification, & genetic drift cells that invalidate research results. They have more than 400 collection centers in India and abroad. One can visit their nearby collection center to give the DNA sample for testing. Moreover, they provide the cell line authentication DNA test report within 10-15 business days.
DNA Forensics Laboratory 